Skin, Mental Health and Why Scientific Research Matters

By Silvia Stanica, Senior Manager, Scientific Communications at DECIEM.

MSc. eHealth and HBSc. Life Science - McMaster University

May 8, 2026

Skin is more than just a surface. It’s our largest organ, a biological barrier, and a visible part of how we move through the world. Increasingly, scientific research shows that skin health and mental wellbeing are deeply interconnected - with each influencing the other in ways that are complex but still not yet fully understood (Soares et al., 2024), (Baskaran et al., 2025) (Salari et al., 2024).

Studies across dermatology and psychology have demonstrated that people living with certain skin conditions may be more likely to experience anxiety and depression.1,2 At the same time, psychological stress may also influence skin through hormonal pathways, leading to irritation, breakouts, and an impacted skin barrier.3 This bidirectional relationship - often referred to as the brain-skin axis - reinforces that skin health cannot be viewed in isolation from mental health.

Research into skin and mental health is growing, but there are still many questions - ones that guide how we innovate and talk about science with our community. Advancing this conversation requires rigorous research, interdisciplinary collaboration, and continued inquiry.


Supporting Research at the Intersection of Skin and Mental Wellbeing

At The Ordinary, science is not only about formulations - it’s about building credibility, scientific literacy, and understanding around the role skin plays in people’s lives. As part of our commitment to advancing evidence-based knowledge, we’ve partnered with the University of Toronto’s Leslie Dan Faculty of Pharmacy to launch the DECIEM Graduate Student Award, supporting research that explores the relationship between skin conditions and mental wellbeing.

Through this award, DECIEM has committed $50,000 over two years to fund a Master’s-level research project led in the Graduate Department of Pharmaceutical Sciences at the University of Toronto. Their research will focus on examining how skin conditions intersect with psychological health - an area of growing scientific and clinical importance.

As Deborah Creatura, Global Director of Scientific Communications at DECIEM, explains:

“As a science-based skincare brand, we recognize the importance of supporting research that speaks to the intersection of skincare and psychological well-being. This initiative reflects our commitment to transparency, integrity, and accessibility to science.”

By supporting independent academic research, our goal is not to offer simplified answers to complex experiences, but to help generate meaningful insights that can inform, educate, and drive future innovation.


Why Academic Partnerships Matter

The University of Toronto’s Leslie Dan Faculty of Pharmacy is one of the world’s leading institutions in pharmacy and pharmaceutical sciences, with deep expertise in clinical and interdisciplinary research. Partnering with academic institutions allows us to contribute to - and learn from - research environments grounded in peer review, scientific rigor, and patient-centred outcomes.

According to Mina Tadrous, pharmacist and researcher at the Leslie Dan Faculty of Pharmacy and supervisor of the project:

“By supporting graduate research in this important area, DECIEM is helping to advance knowledge that has the potential to improve patient care and quality of life for people managing skin conditions and understanding how these conditions might impact mental health.”

This collaboration is part of DECIEM’s broader scientific credentialing and education strategy, which includes guest lectures, panels, mentorship, curriculum consultation, and long-term partnerships across pharmacy, cosmetic science, and biotechnology programs. Together, these efforts aim to strengthen the bridge between academic research and real-world impact.


Key Questions in Skin and Mental Health Research

Research shows that certain skin conditions are associated with higher rates of anxiety, depression, and potentially other mental health concerns as well. This may be due to a combination of biological factors, visible symptoms, and the social and psychological impact of living with a skin condition.

The brain–skin axis refers to the bidirectional communication between the nervous system and the skin. Psychological stress can influence skin function through hormonal and immune pathways, while changes in skin health can also affect emotional wellbeing.

Academic research helps generate independent, peer-reviewed evidence that deepens our understanding of complex biological and psychological interactions. These insights are essential for informing responsible innovation, improving education, and advancing meaningful progress in skin health.


Looking Forward

Understanding skin health means understanding people; not just ingredients or products. Supporting research into the connection between skin conditions and mental wellbeing is one way we can contribute to a more informed, compassionate, and evidence-based future for skincare.

By investing in graduate research and academic collaboration, we hope to help advance the scientific body of knowledge in this area and empower the next generation of researchers whose work will shape how skin health is understood.

Meaningful progress in skincare doesn’t happen in isolation. It happens through science, partnership, and a commitment to understanding the human experience behind skin.

References:

  1. https://pubmed.ncbi.nlm.nih.gov/37898903/

  2. https://pubmed.ncbi.nlm.nih.gov/40395584/

  3. https://pubmed.ncbi.nlm.nih.gov/34631261/